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KMID : 0387420090200040127
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Korean Society of Oriental Neuropsychiatry
2009 Volume.20 No. 4 p.127 ~ p.135
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A Pilot Study about The Effect of Chunwangbosim-dan(天王補心丹) on Heart Rate Variability of Healthy Subjects
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Kang Rae-Yeop
Kim Hyun-Jin
Han Hyo-Jung
Park Eun-Young
Jang Jeong-A
Seo Ho-Seok
Kim Jin-Won
Kang Hyun-Sun
Kim Ji-Hoon
Cho So-Hyun
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Abstract
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Objectives : This study was conducted to assess the effect of Chunwangbosim-dan(CB) on the autonomic nervous system by using heart rate variability measurement.
Methods : The eligible subjects were composed of the healthy female group of ages 25 to 30 years. They were divided into two groups, the CB group(n=16) and the control group(n=16). We measured the heart rate variability respectively for 3 times at 14:00, 16:00, and 17:00. In the CB group, subjects were administered CB at 15:00. For the measurement values, Mean Heart Rate and SDNN(standard deviation of the NN intervals) were used as time domain analysis, and HF(high frequency), LF(low frequency), and LF / HF ratio were used as frequency domain analysis.
Results : The degree of LF changes in the CB group was significantly lower than control group at 1 hour after administration.
Conclusions : We suggest that Chunwangbosim-dan may be useful for stabilization of the autonomic nervous system by controlling sympathetic nerve in healthy people.
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KEYWORD
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Heart rate variability, Chunwangbosim-dan, Autonomic nervous system
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